Audi A6 vs Mercedes-Benz E-Class

2026 Audi A6 vs 2026 Mercedes-Benz E-Class — two rivals compared on efficiency, size, safety and reliability.

Audi A6

2026 Audi A6

Midsize Station WagonsAWD/4WDHybrid/EV
VS0 – 5Mercedes-Benz E-Class wins 5 of 5 categories
Mercedes-Benz E-Class

2026 Mercedes-Benz E-Class

Midsize CarsAWD/4WDHybrid/EV

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The short version

The Mercedes-Benz E-Class is more fuel-efficient: 28 vs 24 MPG combined in its best version.

That works out to about $450 a year less in fuel for the Mercedes-Benz E-Class (EPA estimate, 15,000 miles).

Across all model years since 2005, the Mercedes-Benz E-Class has had fewer recall campaigns (0 vs 33).

The two cars

The 2026 Audi A6 is a midsize station wagon offered with a 3.0L 6-cyl turbo engine, including a hybrid version and all-wheel drive. It measures about 197 inches long and 74 inches wide on a 115-inch wheelbase, with a curb weight of roughly 4,319 lb (4dr Sedan).

The 2026 Mercedes-Benz E-Class is a midsize car offered with 2 engines (2.0L 4-cyl turbo and 3.0L 6-cyl turbo), including a hybrid version and rear-wheel drive and all-wheel drive. It measures about 195 inches long and 75 inches wide on a 117-inch wheelbase, with a curb weight of roughly 5,269 lb (Amg 4dr Sedan).

Buying used? The 2024 A6 and the 2024 E-Class have the fewest problems in our data; avoid the 2019 A6.

Basics

Midsize Station Wagons
Class
Midsize Cars
Hybrid, Premium Gasoline
Fuel
Hybrid, Plug-in Hybrid
3.0L 6-cyl turbo
Engines
2.0L 4-cyl turbo, 3.0L 6-cyl turbo
All-Wheel Drive
Drivetrain
Rear-Wheel Drive, All-Wheel Drive

Efficiency

24 MPG
Best combined MPG
28 MPG
21 city
City / highway MPG (best)
25 city
$3,400
Fuel cost per year (EPA)
$2,950

Performance & space

362 hp
Horsepower (most powerful)
–
194.9 in
Length
194.9 in
74 in
Width
74 in
57.5 in
Height
57.9 in
4,319 lb
Curb weight (lightest)
4,189 lb

Safety & reliability

13
Driver-assist features standard
–
1
Recalls (2026)
0
33
Recalls, all years since 2005
0
9
Owner complaints (latest year)
0

Interest

24,694
Wikipedia views, 30 days
28,957

Buying used

Best used year
Year to avoid
–

Green = clearly better. Prices are not included. How we calculate this →

Which one should you choose?

Choose the Audi A6 if…

It doesn't clearly beat the Mercedes-Benz E-Class on any measure we track.

Choose the Mercedes-Benz E-Class if…

  • You want lower fuel bills (28 vs 24 MPG)
  • You put reliability history first (0 vs 33 recalls since 2005)

Pros & cons of each

2026 Audi A6

  • Hybrid version availableOffered as a hybrid as well as gas.
  • Lots of standard safety tech4 of 5 key driver aids standard on the versions we checked.
  • Premium fuel requiredEvery gasoline version is rated for premium, which raises running costs.

2026 Mercedes-Benz E-Class

  • Hybrid version availableOffered as a hybrid and plug-in hybrid as well as gas.
  • AWD / 4WD available
  • Premium fuel requiredEvery gasoline version is rated for premium, which raises running costs.

Full 2026 Audi A6 specs →Full 2026 Mercedes-Benz E-Class specs →Compare fuel costs for your driving →Compare size & garage fit →